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Vedaprofen

Vedaprofen (PM 150) is a dual-activity small molecule that acts as a COX-1 inhibitor, exerting anti-inflammatory effects by reducing prostaglandin H2 synthesis. It also inhibits the Escherichia coli sliding clamp (DnaN) with an IC50 of 222 μM and a Ki of 131 μM, making it a useful tool for studying bacterial replication and inflammation mechanisms in vitro.

Product Specifications

CAS Number

71109-09-6

Product Name Alternative

Anti-inflammatory drug, Bacterial, COX-1 selective, COX-1, COX, Cyclooxygenase, E. coli, CERM 10202, CERM10202, CERM-10202, NSAID, nonsteroidal, Inhibitor, inhibit, PM 150, Escherichia coli, exudate PGE2, Prostaglandin Receptor, ProstaglandinReceptor, sliding clamp, serum TxB2, PGE2, PM150, PM-150, Quadrisol, Vedaprofen

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Purity

98.12% (May vary between batches)

Solubility

DMSO:50 mg/mL (177.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.08 mM) ; Ethanol:10 mg/mL (35.41 mM) ; DMF:25 mg/mL (88.53 mM)

Smiles

CC (C (O) =O) c1ccc (C2CCCCC2) c2ccccc12

Molecular Formula

C19H22O2

Molecular Weight

282.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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