Fanotaprim
Fanotaprim is a potent and selective dihydrofolate reductase (DHFR) inhibitor, exhibiting strong activity against Toxoplasma gondii (TgDHFR IC50 = 1.57 nM) with high selectivity over human DHFR (196-fold) . This makes it a valuable chemical tool for studying parasitic infections in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2120282-75-7
Product Name Alternative
Toxoplasmosis, survival, VYR 006, VYR006, VYR-006, reductase, DHFR, dhydrofolate, CD-1, Antifolate, Fanotaprim, Inhibitor, inhibit, mice
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Purity
97.37% (May vary between batches)
Solubility
DMSO:25 mg/mL (66.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.28 mM)
Smiles
COc1ncc (cn1) -c1cccc (c1) N1CCN (CC1) c1cnc (N) nc1N
Molecular Formula
C19H22N8O
Molecular Weight
378.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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