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Fanotaprim

Fanotaprim is a potent and selective dihydrofolate reductase (DHFR) inhibitor, exhibiting strong activity against Toxoplasma gondii (TgDHFR IC50 = 1.57 nM) with high selectivity over human DHFR (196-fold) . This makes it a valuable chemical tool for studying parasitic infections in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2120282-75-7

Product Name Alternative

Toxoplasmosis, survival, VYR 006, VYR006, VYR-006, reductase, DHFR, dhydrofolate, CD-1, Antifolate, Fanotaprim, Inhibitor, inhibit, mice

Field of Research

Cell Biology, Metabolism Research, Molecular Biology

Purity

97.37% (May vary between batches)

Solubility

DMSO:25 mg/mL (66.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.28 mM)

Smiles

COc1ncc (cn1) -c1cccc (c1) N1CCN (CC1) c1cnc (N) nc1N

Molecular Formula

C19H22N8O

Molecular Weight

378.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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