XY028-140
XY028-140 is a cereblon-based PROTAC molecule that selectively degrades CDK4 and CDK6, thereby inhibiting their expression and activity. This compound is a useful research tool for investigating cell cycle disruption in cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
2229974-83-6
Product Name Alternative
Cyclin dependent kinase, Cereblon, CDK4, CDK, CDK6, anticancer, inhibit, Inhibitor, XY028 140, XY028140, XY-028-140, XY028-140, PROTACs
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.59% (May vary between batches)
Solubility
DMSO:5 mg/mL (6.57 mM)
Smiles
O=C1N (C=2C (C (C) =C1C (C) =O) =CN=C (NC3=CC=C (C=N3) N4CCN (C (CNC5=C6C (C (=O) N (C6=O) C7C (=O) NC (=O) CC7) =CC=C5) =O) CC4) N2) C8CCCC8
Molecular Formula
C39H40N10O7
Molecular Weight
760.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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