Sesamol
Sesamol (1,3-Benzodioxol-5-ol) is a research compound shown to mitigate lung injury and inflammation in rat models by activating AMPK/Nrf2 pathways and inhibiting NF-κB/MAPK signaling. It also reduces melanogenesis in melan-a cells by downregulating MITF and tyrosinase activity, involving p38 and JNK phosphorylation. This makes it applicable for studying oxidative stress, inflammatory diseases, and skin pigmentation mechanisms in both in vivo and in vitro systems.
Product Specifications
CAS Number
533-31-3
Product Name Alternative
AMPK, Apoptosis, 1,3-Benzodioxol-5-ol, 3,4-Methylenedioxyphenol, Inhibitor, inhibit, Sesamol
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
Chloroform, Dichloromethane, Ethyl Acetate:Soluble; DMSO:70 mg/mL (506.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (72.4 mM)
Smiles
OC1=CC2=C (OCO2) C=C1
Molecular Formula
C7H6O3
Molecular Weight
138.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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