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IPI-9119

IPI-9119 is a potent, orally bioavailable, and irreversible inhibitor of fatty acid synthase (FASN) with an IC50 of 0.3 nM. This small molecule is a valuable research tool for investigating FASN's role in cancer metabolism, supporting both in vitro biochemical assays and in vivo xenograft studies.

Product Specifications

CAS Number

1346564-56-4

Product Name Alternative

22Rv1, AR-FL, AR-V7, C4-2, cancer, castration-resistant, CRPC, inhibit, irreversible, IPI9119, IPI-9119, IPI 9119, Inhibitor, LNCaP-95, LNCaP, orally, FattyAcidSynthase, Fatty Acid Synthase (FASN), Fatty Acid Synthase, prostate

Field of Research

Metabolism Research

Purity

98.86% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.66 mM) ; DMSO:95 mg/mL (191.75 mM)

Smiles

CC (C) N (C (=O) n1nnn (-c2c (F) cccc2F) c1=O) c1ccc (cc1Oc1ccccc1) C (O) =O

Molecular Formula

C24H19F2N5O5

Molecular Weight

495.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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