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3-Deazauridine

3-Deazauridine (NSC-126849) is a uridine analog functioning as a competitive inhibitor of cytidine triphosphate synthetase (CTPS), thereby blocking CTP biosynthesis. This mechanism supports its research use in studying nucleotide metabolism, with applications in antiviral and anticancer investigations across in vitro and in vivo models.

Product Specifications

CAS Number

23205-42-7

Product Name Alternative

Analog, 3Deazauridine, 3-Deazauridine, 3 Deazauridine, NSC126849, NSC-126849, Nucleoside Antimetabolite, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, NSC 126849

Field of Research

Cell Biology, Molecular Biology

Purity

98.55% (May vary between batches)

Solubility

DMF:16 mg/mL (65.79 mM) ; DMSO:45 mg/mL (185.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.22 mM)

Smiles

O[C@H]1[C@@H] (O[C@H] (CO) [C@H]1O) N2C (=O) C=C (O) C=C2

Molecular Formula

C10H13NO6

Molecular Weight

243.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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