3-Deazauridine
3-Deazauridine (NSC-126849) is a uridine analog functioning as a competitive inhibitor of cytidine triphosphate synthetase (CTPS), thereby blocking CTP biosynthesis. This mechanism supports its research use in studying nucleotide metabolism, with applications in antiviral and anticancer investigations across in vitro and in vivo models.
Product Specifications
CAS Number
23205-42-7
Product Name Alternative
Analog, 3Deazauridine, 3-Deazauridine, 3 Deazauridine, NSC126849, NSC-126849, Nucleoside Antimetabolite, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, NSC 126849
Field of Research
Cell Biology, Molecular Biology
Purity
98.55% (May vary between batches)
Solubility
DMF:16 mg/mL (65.79 mM) ; DMSO:45 mg/mL (185.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.22 mM)
Smiles
O[C@H]1[C@@H] (O[C@H] (CO) [C@H]1O) N2C (=O) C=C (O) C=C2
Molecular Formula
C10H13NO6
Molecular Weight
243.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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