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(Rac) -SAR131675

SAR131675 is a highly specific VEGFR-3 tyrosine kinase inhibitor with in vitro IC50 values of 20 nM and 45 nM for kinase activity and autophosphorylation, respectively. Its in vivo antitumor and antimetastatic effects are mediated through the inhibition of lymphangiogenesis and tumor-associated macrophage invasion.

Product Specifications

CAS Number

1092539-44-0

Product Name Alternative

Inhibitor, inhibit, (Rac) SAR131675, (Rac) SAR131675, (Rac) -SAR131675, (Rac) -SAR-131675, SAR131675, SAR-131675, SAR 131675, selective, potent, racemate, Vascular endothelial growth factor receptor, VEGFR3, VEGFR

Field of Research

Cardiovascular Research, Signal Transduction

Purity

98.34% (May vary between batches)

Solubility

DMSO:Slightly soluble

Smiles

CCn1c (N) c (C (=O) NC) c (=O) c2ccc (nc12) C#C[C@@] (C) (O) COC

Molecular Formula

C18H22N4O4

Molecular Weight

358.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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