GNE-477
GNE-477 is a small molecule inhibitor that potently and simultaneously targets both PI3K and mTOR kinases. This dual mechanism makes it a valuable research tool for studying oncogenic signaling pathways in cancer research, applicable in both cellular and animal models of tumorigenesis.
Product Specifications
CAS Number
1032754-81-6
Product Name Alternative
MTOR, inhibit, Inhibitor, Mammalian target of Rapamycin, GNE477, GNE-477, GNE 477, Phosphoinositide 3-kinase, PI3K, PI3Kα
Field of Research
Signal Transduction
Purity
98.88% (May vary between batches)
Solubility
DMSO:6.88 mg/mL (13.63 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.98 mM)
Smiles
Cc1c (CN2CCN (CC2) S (C) (=O) =O) sc2c (nc (nc12) -c1cnc (N) nc1) N1CCOCC1
Molecular Formula
C21H28N8O3S2
Molecular Weight
504.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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