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GDC0084

GDC-0084 (RG7666) is a selective PI3K inhibitor that blocks the PI3K/AKT signaling pathway, suppressing tumor cell proliferation and survival. It is utilized in oncology research for studying pathway biology and has demonstrated antitumor activity in both in vitro assays and in vivo xenograft models.

Product Specifications

CAS Number

1382979-44-3

Product Name Alternative

GDC 0084, GDC0084, GDC-0084, mTOR, Paxalisib, RG 7666, RG7666, RG-7666, PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ

Field of Research

Signal Transduction

Purity

≥95% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:3.83 mg/mL (10.02 mM)

Smiles

CC1 (C) OCCn2c1nc1c (nc (nc21) -c1cnc (N) nc1) N1CCOCC1

Molecular Formula

C18H22N8O2

Molecular Weight

382.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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