GDC0084
GDC-0084 (RG7666) is a selective PI3K inhibitor that blocks the PI3K/AKT signaling pathway, suppressing tumor cell proliferation and survival. It is utilized in oncology research for studying pathway biology and has demonstrated antitumor activity in both in vitro assays and in vivo xenograft models.
Product Specifications
CAS Number
1382979-44-3
Product Name Alternative
GDC 0084, GDC0084, GDC-0084, mTOR, Paxalisib, RG 7666, RG7666, RG-7666, PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ
Field of Research
Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:3.83 mg/mL (10.02 mM)
Smiles
CC1 (C) OCCn2c1nc1c (nc (nc21) -c1cnc (N) nc1) N1CCOCC1
Molecular Formula
C18H22N8O2
Molecular Weight
382.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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