BP-1-102

BP-1-102 is a potent and selective oral STAT3 inhibitor that disrupts STAT3 activation by binding with high affinity (Kd: 504 nM) . It effectively suppresses the growth, survival, and invasion of STAT3-dependent cancer cells in vitro by downregulating key oncogenic targets like c-Myc and VEGF, and has demonstrated antitumor efficacy in vivo models.

Product Specifications

CAS Number

1334493-07-0

Product Name Alternative

BP 1 102, BP1102, BP-1-102, Inhibitor, inhibit, STAT, STAT3

Field of Research

Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.61% (May vary between batches)

Solubility

DMSO:93 mg/mL (148.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.27 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)