BP-1-102
BP-1-102 is a potent and selective oral STAT3 inhibitor that disrupts STAT3 activation by binding with high affinity (Kd: 504 nM) . It effectively suppresses the growth, survival, and invasion of STAT3-dependent cancer cells in vitro by downregulating key oncogenic targets like c-Myc and VEGF, and has demonstrated antitumor efficacy in vivo models.
Product Specifications
CAS Number
1334493-07-0
Product Name Alternative
BP 1 102, BP1102, BP-1-102, Inhibitor, inhibit, STAT, STAT3
Field of Research
Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.61% (May vary between batches)
Solubility
DMSO:93 mg/mL (148.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.27 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN (CC (=O) N (Cc1ccc (cc1) C1CCCCC1) c1ccc (C (O) =O) c (O) c1) S (=O) (=O) c1c (F) c (F) c (F) c (F) c1F
Molecular Formula
C29H27F5N2O6S
Molecular Weight
626.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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