RAF709
RAF709 is a potent and selective small molecule inhibitor of Raf kinases, exhibiting sub-nanomolar IC50 values against c-Raf (0.5 nM) and b-Raf (1.8 nM) . It is a valuable research tool for investigating the MAPK/ERK signaling pathway in both cellular and in vivo models of cancer and proliferative diseases.
Product Specifications
CAS Number
1628838-42-5
Product Name Alternative
C-Raf, B-Raf, Inhibitor, inhibit, Raf, RAF 709, Raf kinases, RAF709, RAF-709
Field of Research
Signal Transduction
Purity
99.28% (May vary between batches)
Solubility
DMSO:91 mg/mL (167.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.08 mM)
Smiles
Cc1ncc (NC (=O) c2cccc (c2) C (F) (F) F) cc1-c1cnc (OC2CCOCC2) c (c1) N1CCOCC1
Molecular Formula
C28H29F3N4O4
Molecular Weight
542.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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