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K-Ras (G12C) inhibitor 6

This small molecule is an irreversible, allosteric inhibitor of the K-Ras (G12C) mutant. It achieves complete target occupancy in vitro and is a key tool for investigating mutant KRAS-driven oncology in both cellular and animal model studies.

Product Specifications

CAS Number

2060530-16-5

Product Name Alternative

K Ras (G12C) Inhibitor 6, K-Ras, KRas (G12C) Inhibitor 6, K-Ras (G12C) inhibitor 6, K-Ras (G12C) Inhibitor 6, K-Ras (G-12C) Inhibitor 6, inhibit, Inhibitor, Ras

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

89.07% (May vary between batches)

Solubility

DMSO:73 mg/mL (180.1 mM)

Smiles

SCCCC (=O) NC1CCN (CC1) C (=O) COc1ccc (Cl) cc1Cl

Molecular Formula

C17H22Cl2N2O3S

Molecular Weight

405.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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