CAY10781
CAY10781 is a small molecule inhibitor that disrupts the NRP-1/VEGF-A interaction, showing 43% inhibition at 12.5 μM. This compound also reduces VEGF-A-induced VEGFR2 phosphorylation in differentiated CAD cells, making it a useful research tool for studying angiogenesis in cancer and vascular biology models.
Product Specifications
CAS Number
1210360-87-4
Product Name Alternative
CAY10781, CAY-10781, CAY 10781
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.69% (May vary between batches)
Solubility
Ethanol:Insoluble; DMF:Insoluble; PBS (pH 7.2) :Insoluble; DMSO:10 mg/mL (43.25 mM)
Smiles
OC (=O) CC1=CNC (=NC1=O) C1=CN=CC=C1
Molecular Formula
C11H9N3O3
Molecular Weight
231.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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