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CAY10781

CAY10781 is a small molecule inhibitor that disrupts the NRP-1/VEGF-A interaction, showing 43% inhibition at 12.5 μM. This compound also reduces VEGF-A-induced VEGFR2 phosphorylation in differentiated CAD cells, making it a useful research tool for studying angiogenesis in cancer and vascular biology models.

Product Specifications

CAS Number

1210360-87-4

Product Name Alternative

CAY10781, CAY-10781, CAY 10781

Field of Research

Cardiovascular Research, Signal Transduction

Purity

98.69% (May vary between batches)

Solubility

Ethanol:Insoluble; DMF:Insoluble; PBS (pH 7.2) :Insoluble; DMSO:10 mg/mL (43.25 mM)

Smiles

OC (=O) CC1=CNC (=NC1=O) C1=CN=CC=C1

Molecular Formula

C11H9N3O3

Molecular Weight

231.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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