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2,2,2-Trichloroethanol

2,2,2-Trichloroethanol is a chemical activator of the mechanosensitive two-pore domain potassium channels TREK-1 and TRAAK. This compound is a valuable research tool for investigating the roles of these K2P channels in pain sensation, neuroprotection, and depression in both cellular and animal models.

Product Specifications

CAS Number

115-20-8

Product Name Alternative

Endogenous Metabolite, EndogenousMetabolite, hydrate, Human Endogenous Metabolite, hypnotic, Inhibitor, KcsA, KCNK2, KCNK4, inhibit, K (+), nonclassical, non-classical, 2,2,2Trichloroethanol, 2,2,2-Trichloroethanol, 2,2,2 Trichloroethanol, channel, channels, chloral, TREK-1, TRAAK, Potassium Channel, potassium, PotassiumChannel

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

97.56% (May vary between batches)

Solubility

DMSO:55 mg/mL (368.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (13.39 mM)

Smiles

OCC (Cl) (Cl) Cl

Molecular Formula

C2H3Cl3O

Molecular Weight

149.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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