2,2,2-Trichloroethanol
2,2,2-Trichloroethanol is a chemical activator of the mechanosensitive two-pore domain potassium channels TREK-1 and TRAAK. This compound is a valuable research tool for investigating the roles of these K2P channels in pain sensation, neuroprotection, and depression in both cellular and animal models.
Product Specifications
CAS Number
115-20-8
Product Name Alternative
Endogenous Metabolite, EndogenousMetabolite, hydrate, Human Endogenous Metabolite, hypnotic, Inhibitor, KcsA, KCNK2, KCNK4, inhibit, K (+), nonclassical, non-classical, 2,2,2Trichloroethanol, 2,2,2-Trichloroethanol, 2,2,2 Trichloroethanol, channel, channels, chloral, TREK-1, TRAAK, Potassium Channel, potassium, PotassiumChannel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.56% (May vary between batches)
Solubility
DMSO:55 mg/mL (368.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (13.39 mM)
Smiles
OCC (Cl) (Cl) Cl
Molecular Formula
C2H3Cl3O
Molecular Weight
149.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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