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Methyl protodioscin

Methyl protodioscin, a steroidal saponin, demonstrates potential cardioprotective effects by modulating cholesterol levels and exhibits antitumor activity. Its pro-apoptotic mechanism in vitro, studied in human A549 lung carcinoma cells, involves disrupting mitochondrial membrane potential and activating caspase-3 via cytochrome c release.

Product Specifications

CAS Number

54522-52-0

Product Name Alternative

Inhibitor, NSC 698790, inhibit, Methyl protodioscin, NSC698790, NSC-698790, Apoptosis inducer, Apoptosis, Smilax saponin B

Field of Research

Cell Biology

Purity

99.24% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.1 mM) ; DMSO:16.67 mg/mL (15.68 mM)

Smiles

[H][C@]12C[C@@]3 ([H]) [C@]4 ([H]) CC=C5C[C@H] (CC[C@]5 (C) [C@@]4 ([H]) CC[C@]3 (C) [C@@]1 ([H]) [C@H] (C) [C@] (CC[C@@H] (C) CO[C@@H]1O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]1O) (OC) O2) O[C@]1 ([H]) O[C@H] (CO) [C@@H] (O[C@]2 ([H]) O[C@@H] (C) [C@H] (O) [C@@H] (O) [C@H]2O) [C@H] (O) [C@H]1O[C@]1 ([H]) O[C@@H] (C) [C@H] (O) [C@@H] (O) [C@H]1O

Molecular Formula

C52H86O22

Molecular Weight

1063.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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