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AMPA receptor modulator-2

AMPA receptor modulator-2 is a potent positive allosteric modulator of AMPA receptors, exhibiting a pIC50 of 10.1 in a TARPγ2-dependent assay. This compound is a valuable research tool for investigating synaptic plasticity, learning, and memory in both cellular and animal models of neurological function.

Product Specifications

CAS Number

2034181-36-5

Product Name Alternative

AMPA, AMPA receptor modulator2, AMPA receptor modulator-2, AMPA receptor modulator 2, iGluR, Inhibitor, inhibit, Ionotropic glutamate receptors, TARPγ

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.62% (May vary between batches)

Solubility

DMSO:250 mg/mL (618.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.37 mM) ; H2O:< 0.1 mg/mL (insoluble)

Smiles

FC (F) (F) c1nc2ccc (nc2n1-c1ccc2[nH]c (=O) sc2c1) C (F) (F) F

Molecular Formula

C15H6F6N4OS

Molecular Weight

404.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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