A2A receptor antagonist 1
This compound is a dual adenosine receptor antagonist, exhibiting high affinity for the A2A receptor (Ki = 4 nM) and moderate affinity for the A1 receptor (Ki = 264 nM) . As a CPI-444 analog, it is a valuable research tool for investigating adenosine signaling in oncology and immunology, supporting both in vitro binding assays and in vivo tumor model studies.
Product Specifications
CAS Number
443103-97-7
Product Name Alternative
A2A receptor antagonist 1, A2A/A1, AdenosineReceptor, Adenosine Receptor, CPI 444, CPI444, CPI-444, CPI-444 analog, disease, model, Parkinson, inhibit, Inhibitor, hypolocomotion, P1 receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.29% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.47 mM) ; DMSO:50 mg/mL (161.66 mM)
Smiles
Nc1nc (-c2ccco2) c2cnn (Cc3ccccc3F) c2n1
Molecular Formula
C16H12FN5O
Molecular Weight
309.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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