Isosilybin
Isosilybin and Silybin are potential PXR antagonists for research, aimed at mitigating CYP3A4-mediated drug-drug interactions. Studies in vitro and in vivo support their application in oncology research for improving therapeutic safety by modulating nuclear receptor pathways.
Product Specifications
CAS Number
72581-71-6
Product Name Alternative
CYP3A4, Cytochrome P450, Isosilibinin, Isosilybin, Isosilybinin, Q100795, Q 100795
Field of Research
Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
Chloroform, Dichloromethane, Ethyl Acetate:Soluble; DMSO:88 mg/mL (182.41 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.84 mM)
Smiles
COc1cc (ccc1O) C1Oc2ccc (cc2OC1CO) C1Oc2cc (O) cc (O) c2C (=O) [C@@H]1O
Molecular Formula
C25H22O10
Molecular Weight
482.44
Storage Conditions
-20°C
Notes
For research use only.
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