Specnuezhenide
Specnuezhenide (Nuezhenide) is a natural compound derived from Ligustrum lucidum fruit. It demonstrates anti-inflammatory activity by inhibiting NF-κB and Wnt/β-catenin signaling pathways, as shown in IL-1β-stimulated chondrocyte studies. This mechanism underlies its protective effects observed in rat models of osteoarthritis.
Product Specifications
CAS Number
39011-92-2
Product Name Alternative
Inhibit, Inhibitor, Nuclear factor-kappaB, Nuclear factor-κB, Nuzhenide, Nuezhenide, NF-κB, NF-kB, NFkB, NFκB, bcatenin, anti-angiogenic, (8E) -Nuezhenide, diabetic retinopathy, betacatenin, beta-catenin, βcatenin, Wnt/β-catenin, Wnt/b-catenin, Wnt, Wnt/betacatenin, osteoarthritis, Specnuezhenide
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:137.5 mg/mL (200.24 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.28 mM)
Smiles
COC (=O) C1=CO[C@@H] (O[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]2O) \C (=C\C) [C@@H]1CC (=O) OC[C@H]1O[C@@H] (OCCc2ccc (O) cc2) [C@H] (O) [C@@H] (O) [C@@H]1O
Molecular Formula
C31H42O17
Molecular Weight
686.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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