ML-148
ML-148 is a potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 56 nM. This compound is a valuable chemical probe for studying prostaglandin signaling pathways in vitro and has been utilized in research exploring tissue regeneration and hematopoietic recovery in vivo.
Product Specifications
CAS Number
451496-96-1
Product Name Alternative
PGE2, selective, prostaglandin-signaling, Inhibitor, inhibit, ML 148, ML148, ML-148, NAD+, 15-PGDH, 15-Hydroxyprostaglandin dehydrogenase
Field of Research
Metabolism Research
Purity
99.81% (May vary between batches)
Solubility
DMSO:11 mg/mL (34.44 mM) ; DMF:PBS (pH 7.2) (1:1) :0.5 mg/mL (1.57 mM) ; DMF:25 mg/mL (78.27 mM) ; Ethanol:10 mg/mL (31.31 mM)
Smiles
Cc1cccc (c1) -n1cnc2cc (ccc12) C (=O) N1CCCCC1
Molecular Formula
C20H21N3O
Molecular Weight
319.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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