GSK717
GSK717 is a potent, selective NOD2 inhibitor that disrupts its synergistic signaling with TLR2 while sparing NOD1, TNFR1, and direct TLR2 pathways. This tool compound is valuable for in vitro and in vivo research investigating NOD2's role in inflammatory and autoimmune diseases.
Product Specifications
CAS Number
1595278-21-9
Product Name Alternative
Cytokines, inhibit, immune, IL-8, ILReceptor, NOD2, NOD2-TLR2, NOD-like Receptor (NLR), GSK 717, GSK717, GSK-717, Inhibitor, IL Receptor, MDP-stimulated, pro-inflammatory, responses, synergy
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
97.34% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.05 mM) ; DMSO:250 mg/mL (552.43 mM)
Smiles
CN (CCc1nc2ccccc2n1CC (=O) Nc1ccc2CCCc2c1) C (=O) c1ccccc1
Molecular Formula
C28H28N4O2
Molecular Weight
452.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6396196-01 0.1 mL
TCF19 (Transcription Factor 19, TCF-19, SC1, SC1-1, Transcription Factor SC1) (HRP)
Sign In for Pricing
View Details MBS6396196-02 5x 0.1 mL
TCF19 (Transcription Factor 19, TCF-19, SC1, SC1-1, Transcription Factor SC1) (HRP)
Sign In for Pricing
View Details 17257061 1.0 µg DNA
CYCSP17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
abx309161-01 20 µg
Ecto-ADP-Ribosyltransferase 14 (ART5) Antibody (Biotin)
Sign In for Pricing
View Details abx309161-02 50 µg
Ecto-ADP-Ribosyltransferase 14 (ART5) Antibody (Biotin)
Sign In for Pricing
View Details