CL097
CL097 is a potent dual agonist of TLR7 and TLR8, known to trigger pro-inflammatory cytokine release and prime NADPH oxidase in macrophages. This priming enhances fMLF-stimulated reactive oxygen species (ROS) production, making it a valuable tool for studying innate immune responses, inflammation, and oxidative burst mechanisms in both cellular and animal models.
Product Specifications
CAS Number
1026249-18-2
Product Name Alternative
Heterocycle, Inhibitor, Immunological, inhibit, Oligonucleotide, modulators, CL 097, CL097, CL-097, Peptide, Reactive Oxygen Species, TLR8, TLR7, ReactiveOxygenSpecies, Toll-like Receptor (TLR)
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
99.57% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (13.62 mM) ; DMSO:95 mg/mL (392.11 mM)
Smiles
CCOCc1nc2c ([nH]1) c (N) nc1ccccc21
Molecular Formula
C13H14N4O
Molecular Weight
242.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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