AKN-028
AKN-028 is a potent and orally bioavailable small molecule inhibitor of FLT3 tyrosine kinase, demonstrating an IC50 of 6 nM. It effectively suppresses FLT3 autophosphorylation in a dose-dependent manner and is utilized in preclinical research for investigating acute myeloid leukemia (AML) in both cellular and animal models.
Product Specifications
CAS Number
1175017-90-9
Product Name Alternative
Fms like tyrosine kinase 3, FLT3 autophosphorylation, FLT3, inhibit, Inhibitor, CD135, Cluster of differentiation antigen 135, cytotoxic, Apoptosis, AML cell lines, Caspase, AKN 028, AKN028, AKN-028, acute myeloid leukemia
Field of Research
Cardiovascular Research, Cell Biology, Protein Biochemistry, Signal Transduction
Purity
97.30% (May vary between batches)
Solubility
DMSO:20 mg/mL (66.15 mM)
Smiles
N (C=1N=C (C=NC1N) C=2C=CN=CC2) C=3C=C4C (=CC3) NC=C4
Molecular Formula
C17H14N6
Molecular Weight
302.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal SLC30A3 Antibody [DyLight 488]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP2-97660G 0.1 mL
Rabbit Polyclonal SLC30A3 Antibody [DyLight 488]
Sign In for Pricing
View Details 
bs-19301R-BF647 100 µL
Phospho-nNOS (Ser1417) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Sign In for Pricing
View Details MR206968L4V 200 µL
Etf1 (NM_144866) Mouse Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
MBS1241014 Inquire
Recombinant Sphingomonas wittichii Prolipoprotein diacylglyceryl transferase (lgt)
Sign In for Pricing
View Details