Isoliquiritin apioside
Isoliquiritin apioside, a compound from Glycyrrhizae radix, inhibits PMA-induced MMP9 activity, MAPK/NF-κB signaling, and reduces cancer cell invasiveness and angiogenesis. It also shows potential against oxidative stress-induced genotoxicity, supporting its use in oncology and molecular pharmacology research for in vitro mechanistic studies.
Product Specifications
CAS Number
120926-46-7
Product Name Alternative
P38MAPK, p38 MAPK, Isoliquiritin apioside, Inhibitor, inhibit, NF-kB, NFκB, NFkB, MMP, Nuclear factor-κB, Nuclear factor-kappaB, NF-κB, metastasis, HT1080, HIF-1α, MAPK, Matrix metalloproteinases, angiogenesis, cancer
Field of Research
Protein Biochemistry, Signal Transduction
Purity
98.84% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.63 mM) ; DMSO:33.3 mg/mL (60.49 mM)
Smiles
[H][C@]1 (O[C@@H]2OC[C@] (O) (CO) [C@H]2O) [C@H] (Oc2ccc (\C=C\C (=O) c3ccc (O) cc3O) cc2) O[C@H] (CO) [C@@H] (O) [C@@H]1O
Molecular Formula
C26H30O13
Molecular Weight
550.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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