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Chikusetsusaponin IVa

Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator that stimulates insulin secretion in βTC3 cells via GPR4-mediated calcium and PKC signaling. This activity suggests its potential as a research tool for investigating type 2 diabetes mellitus (T2DM) pathways in cellular models.

Product Specifications

CAS Number

51415-02-2

Product Name Alternative

Inhibitor, inhibit, AMPK, Chikusetsusaponin IVa, Calenduloside F

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction

Purity

98.46% (May vary between batches)

Solubility

DMSO:60 mg/mL (75.47 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.52 mM)

Smiles

CC1 (C) CC[C@@]2 (CC[C@]3 (C) C (=CC[C@@H]4[C@@]5 (C) CC[C@H] (O[C@@H]6O[C@@H] ([C@@H] (O) [C@H] (O) [C@H]6O) C (O) =O) C (C) (C) [C@@H]5CC[C@@]34C) [C@@H]2C1) C (=O) O[C@@H]1O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]1O

Molecular Formula

C42H66O14

Molecular Weight

794.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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