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AKR1C3-IN-4

AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibiting an IC50 of 0.56 μM. This compound is a valuable research tool for studying castrate-resistant prostate cancer (CRPC), with applications in both in vitro enzymatic assays and in vivo xenograft models to investigate androgen biosynthesis pathways.

Product Specifications

CAS Number

1284180-11-5

Product Name Alternative

Resistant, prostate, reductase, castrate, CRPC, cancer, AKR1C2, AKR1C3, AKR1C3 IN 4, AKR1C3IN4, aldo-keto, AKR-1C3-IN-4, AKR1C3-IN-4, 1C3, Inhibitor, inhibit

Field of Research

Metabolism Research

Purity

98.59% (May vary between batches)

Solubility

DMSO:100 mg/mL (355.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.22 mM)

Smiles

OC (=O) c1cccc (Nc2ccc (cc2) C (F) (F) F) c1

Molecular Formula

C14H10F3NO2

Molecular Weight

281.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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