AKR1C3-IN-4
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibiting an IC50 of 0.56 μM. This compound is a valuable research tool for studying castrate-resistant prostate cancer (CRPC), with applications in both in vitro enzymatic assays and in vivo xenograft models to investigate androgen biosynthesis pathways.
Product Specifications
CAS Number
1284180-11-5
Product Name Alternative
Resistant, prostate, reductase, castrate, CRPC, cancer, AKR1C2, AKR1C3, AKR1C3 IN 4, AKR1C3IN4, aldo-keto, AKR-1C3-IN-4, AKR1C3-IN-4, 1C3, Inhibitor, inhibit
Field of Research
Metabolism Research
Purity
98.59% (May vary between batches)
Solubility
DMSO:100 mg/mL (355.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.22 mM)
Smiles
OC (=O) c1cccc (Nc2ccc (cc2) C (F) (F) F) c1
Molecular Formula
C14H10F3NO2
Molecular Weight
281.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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