LP-922056
LP-922056 is a potent and selective inhibitor of Notum Pectinacetylesterase, demonstrating EC50 values of 21 nM for human and 55 nM for mouse enzymes. This small molecule is a valuable research tool for investigating Wnt signaling modulation in both cellular and animal models of bone regeneration and metabolic disorders.
Product Specifications
CAS Number
1365060-22-5
Product Name Alternative
Thickness, Wnt, Wnt/betacatenin, Wnt/b-catenin, Wnt/β-catenin, βcatenin, betacatenin, beta-catenin, cortical, bone, bcatenin, Inhibitor, femur, lipase, Notum, LP922056, LP-922056, LP 922056, inhibit, orally, Pectinacetylesterase, midshaft
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.84% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.3 mM) ; DMSO:120 mg/mL (398.96 mM)
Smiles
OC (=O) CSc1ncnc2c (C3CC3) c (Cl) sc12
Molecular Formula
C11H9ClN2O2S2
Molecular Weight
300.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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