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Neoandrographolide

Neoandrographolide is a bioactive small molecule with significant hypolipidemic and cardiovascular protective effects, showing minimal hepatotoxicity. Its anti-inflammatory activity involves suppressing iNOS and COX-2 via p38 MAPK inhibition. Furthermore, it acts as a chemosensitizer in vitro, overcoming chemoresistance in models like XIAP-overexpressing Jurkat cells.

Product Specifications

CAS Number

27215-14-1

Product Name Alternative

INOS, Inhibitor, Neoandrographiside, Neoandrographolide, inhibit, COX-2

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.52% (May vary between batches)

Solubility

DMSO:50 mg/mL (104.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (20.81 mM)

Smiles

C[C@@]1 (CO[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]2O) CCC[C@@]2 (C) [C@H] (CCC3=CCOC3=O) C (=C) CC[C@H]12

Molecular Formula

C26H40O8

Molecular Weight

480.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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