Neoandrographolide
Neoandrographolide is a bioactive small molecule with significant hypolipidemic and cardiovascular protective effects, showing minimal hepatotoxicity. Its anti-inflammatory activity involves suppressing iNOS and COX-2 via p38 MAPK inhibition. Furthermore, it acts as a chemosensitizer in vitro, overcoming chemoresistance in models like XIAP-overexpressing Jurkat cells.
Product Specifications
CAS Number
27215-14-1
Product Name Alternative
INOS, Inhibitor, Neoandrographiside, Neoandrographolide, inhibit, COX-2
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.52% (May vary between batches)
Solubility
DMSO:50 mg/mL (104.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (20.81 mM)
Smiles
C[C@@]1 (CO[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]2O) CCC[C@@]2 (C) [C@H] (CCC3=CCOC3=O) C (=C) CC[C@H]12
Molecular Formula
C26H40O8
Molecular Weight
480.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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