Ginsenoside Rb3
Ginsenoside Rb3 (Gypenoside IV) is a triterpenoid saponin that suppresses TNFα-induced NF-κB activation, thereby reducing COX-2 and iNOS mRNA expression. This mechanism supports its research applications in studying inflammation, cancer, and metabolic diseases in both cellular and animal models.
Product Specifications
CAS Number
68406-26-8
Product Name Alternative
COX, Cyclooxygenase, Nitric oxide synthases, NF-κB, NO Synthase, Nuclear factor-kappaB, Nuclear factor-κB, NFκB, NFkB, NF-kB, inhibit, NOS, NOSynthase, Ginsenoside Rb 3, Ginsenoside Rb3, Ginsenoside Rb-3, Gypenoside IV, Inhibitor
Field of Research
Immunology & Inflammation, Neuroscience, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:125 mg/mL (115.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.85 mM)
Smiles
CC (C) =CCC[C@@] (C) (O[C@@H]1O[C@H] (CO[C@@H]2OC[C@@H] (O) [C@H] (O) [C@H]2O) [C@@H] (O) [C@H] (O) [C@H]1O) [C@H]1CC[C@]2 (C) [C@@H]1[C@H] (O) C[C@@H]1[C@@]3 (C) CC[C@H] (O[C@@H]4O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]4O[C@@H]4O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]4O) C (C) (C) [C@@H]3CC[C@@]21C
Molecular Formula
C53H90O22
Molecular Weight
1079.27
Storage Conditions
-20°C
Notes
For research use only.
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