Befotertinib
Befotertinib (D-0316) is a third-generation EGFR tyrosine kinase inhibitor designed to target the T790M resistance mutation. It is a research compound used in preclinical studies, including in vitro cellular assays and in vivo models, for non-small cell lung cancer (NSCLC) .
Product Specifications
CAS Number
1835667-63-4
Product Name Alternative
D 0316, D0316, D-0316, Befotertinib, cancer, EGFR, Epidermal growth factor receptor, ErbB-1, Inhibitor, HER1, inhibit, kinase, non-small, NSCLC, lung, tyrosine
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.40% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.52 mM) ; DMSO:60 mg/mL (105.71 mM)
Smiles
COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1nccc (n1) -c1cn (CC (F) (F) F) c2ccccc12
Molecular Formula
C29H32F3N7O2
Molecular Weight
567.61
Storage Conditions
-20°C
Notes
For research use only.
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