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Befotertinib

Befotertinib (D-0316) is a third-generation EGFR tyrosine kinase inhibitor designed to target the T790M resistance mutation. It is a research compound used in preclinical studies, including in vitro cellular assays and in vivo models, for non-small cell lung cancer (NSCLC) .

Product Specifications

CAS Number

1835667-63-4

Product Name Alternative

D 0316, D0316, D-0316, Befotertinib, cancer, EGFR, Epidermal growth factor receptor, ErbB-1, Inhibitor, HER1, inhibit, kinase, non-small, NSCLC, lung, tyrosine

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.40% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.52 mM) ; DMSO:60 mg/mL (105.71 mM)

Smiles

COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1nccc (n1) -c1cn (CC (F) (F) F) c2ccccc12

Molecular Formula

C29H32F3N7O2

Molecular Weight

567.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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