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RMC-4630

RMC-4630 (SHP2-IN-7) is a potent and selective allosteric inhibitor of the SHP2 phosphatase. It is a valuable research tool for investigating oncogenic signaling pathways in vitro and has demonstrated antitumor activity in preclinical in vivo models for cancer research.

Product Specifications

CAS Number

2172652-48-9

Product Name Alternative

Inhibitor, inhibit, SHP2-IN-7, SHP-2, Phosphatase, RMC 4630, RMC4630, RMC-4630

Field of Research

Metabolism Research

Purity

97.16% (May vary between batches)

Solubility

DMSO:45 mg/mL (99.78 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.43 mM)

Smiles

C[C@@H]1OCC2 (CCN (CC2) c2nc (C) c (Sc3ccnc (N) c3Cl) nc2CO) [C@@H]1N

Molecular Formula

C20H27ClN6O2S

Molecular Weight

450.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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