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AZD9496

AZD9496 is an orally bioavailable, selective antagonist of estrogen receptor alpha (ERα) with potential antitumor activity. It has demonstrated efficacy in inhibiting the growth of ER-positive breast cancer cells in vitro and in xenograft models in vivo.

Product Specifications

CAS Number

1639042-08-2

Product Name Alternative

AZD9496, AZD-9496, AZD 9496, inhibit, Inhibitor, Estrogen Receptor, Estrogen Receptor/ERR, EstrogenReceptor, ERα, ERR, progestogen Receptor, progestogenReceptor

Field of Research

Metabolism Research

Purity

97.28% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:125 mg/mL (282.51 mM) ; Ethanol:82 mg/mL (185.32 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.46 mM)

Smiles

C (C (C) (C) F) N1[C@@H] (C2=C (C=3C (N2) =CC=CC3) C[C@H]1C) C4=C (F) C=C (/C=C/C (O) =O) C=C4F

Molecular Formula

C25H25F3N2O2

Molecular Weight

442.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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