CDK12-IN-2
CDK12-IN-2 is a potent and selective CDK12 inhibitor with an IC50 of 52 nM, demonstrating >1000-fold selectivity over CDK2, CDK7, and CDK9. This tool compound is widely used in vitro to investigate CDK12's role in transcription regulation and DNA damage response pathways.
Product Specifications
CAS Number
2244987-03-7
Product Name Alternative
CDK12 inhibitor 2, CDK12-IN-2, CDK12
Field of Research
Cell Biology, Signal Transduction
Purity
98.61% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (4.69 mM) ; DMSO:50 mg/mL (93.87 mM)
Smiles
Cn1cc (ccc1=O) -c1ccc (cc1) N ([C@H]1CC[C@@H] (CC1) Nc1ccc (cn1) C#N) C (=O) NCc1ccccc1
Molecular Formula
C32H32N6O2
Molecular Weight
532.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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