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CDK12-IN-2

CDK12-IN-2 is a potent and selective CDK12 inhibitor with an IC50 of 52 nM, demonstrating >1000-fold selectivity over CDK2, CDK7, and CDK9. This tool compound is widely used in vitro to investigate CDK12's role in transcription regulation and DNA damage response pathways.

Product Specifications

CAS Number

2244987-03-7

Product Name Alternative

CDK12 inhibitor 2, CDK12-IN-2, CDK12

Field of Research

Cell Biology, Signal Transduction

Purity

98.61% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2.5 mg/mL (4.69 mM) ; DMSO:50 mg/mL (93.87 mM)

Smiles

Cn1cc (ccc1=O) -c1ccc (cc1) N ([C@H]1CC[C@@H] (CC1) Nc1ccc (cn1) C#N) C (=O) NCc1ccccc1

Molecular Formula

C32H32N6O2

Molecular Weight

532.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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