Lifitegrast
Lifitegrast (SAR 1118) is a small molecule antagonist of lymphocyte function-associated antigen-1 (LFA-1) . It is used in research to investigate cell adhesion and immune signaling pathways, with applications in studying inflammatory conditions such as dry eye disease in both in vitro and in vivo models.
Product Specifications
CAS Number
1025967-78-5
Product Name Alternative
ICAM-1, Integrin, Inhibitor, LFA-1, inflammatory cycle, Lifitegrast, Jurkat T, inhibit, dry eye disease, T cell, SAR1118, SAR-1118, SAR 1118, SHP 606, SHP606, SHP-606
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.39% (May vary between batches)
Solubility
DMSO:245 mg/mL (398.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.25 mM)
Smiles
CS (=O) (=O) c1cccc (C[C@H] (NC (=O) c2c (Cl) cc3CN (CCc3c2Cl) C (=O) c2ccc3ccoc3c2) C (O) =O) c1
Molecular Formula
C29H24Cl2N2O7S
Molecular Weight
615.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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