Desmorpholinyl Navitoclax-NH-Me
Desmorpholinyl Navitoclax-NH-Me is a potent and selective Bcl-xL inhibitor. This compound serves as a key precursor for constructing PROTAC degraders like XZ739, enabling the targeted degradation of BCL-XL protein in cancer research for both in vitro and in vivo studies.
Product Specifications
CAS Number
2365172-82-1
Product Name Alternative
Target Protein-binding Moiety, Desmorpholinyl ABT-263-NH-Me, Desmorpholinyl Navitoclax NH Me, Desmorpholinyl NavitoclaxNHMe, Desmorpholinyl Navitoclax-NH-Me, Bcl-2 Family, Ligands for Target Protein for PROTAC, inhibit, Inhibitor
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
99.87% (May vary between batches)
Solubility
DMSO:100 mg/mL (108.87 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (3.59 mM)
Smiles
CNCC[C@H] (CSc1ccccc1) Nc1ccc (cc1S (=O) (=O) C (F) (F) F) S (=O) (=O) NC (=O) c1ccc (cc1) N1CCN (CC2=C (CCC (C) (C) C2) c2ccc (Cl) cc2) CC1
Molecular Formula
C44H51ClF3N5O5S3
Molecular Weight
918.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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