Amcasertib
Amcasertib (BBI503) is an oral small molecule inhibitor targeting stemness kinases to disrupt cancer stem cell pathways. It has demonstrated activity in preclinical in vitro and in vivo studies across various cancer types, including colon and breast cancer models, supporting its investigation as an anti-cancer stem cell therapeutic.
Product Specifications
CAS Number
1129403-56-0
Product Name Alternative
BBI 503, BBI503, BBI-503, Amcasertib, inhibit, Inhibitor, Stemness kinase, Stemnesskinase
Field of Research
Cell Biology, Stem Cell & Developmental Biology
Purity
97.10% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.85 mM) ; DMSO:5.4 mg/mL (10.01 mM)
Smiles
CCN (CC) CCNC (=O) c1c (C) [nH]c (\C=C2\C (=O) Nc3ccc (cc23) -c2csc (n2) -c2ccccc2) c1C
Molecular Formula
C31H33N5O2S
Molecular Weight
539.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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