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Amcasertib

Amcasertib (BBI503) is an oral small molecule inhibitor targeting stemness kinases to disrupt cancer stem cell pathways. It has demonstrated activity in preclinical in vitro and in vivo studies across various cancer types, including colon and breast cancer models, supporting its investigation as an anti-cancer stem cell therapeutic.

Product Specifications

CAS Number

1129403-56-0

Product Name Alternative

BBI 503, BBI503, BBI-503, Amcasertib, inhibit, Inhibitor, Stemness kinase, Stemnesskinase

Field of Research

Cell Biology, Stem Cell & Developmental Biology

Purity

97.10% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.85 mM) ; DMSO:5.4 mg/mL (10.01 mM)

Smiles

CCN (CC) CCNC (=O) c1c (C) [nH]c (\C=C2\C (=O) Nc3ccc (cc23) -c2csc (n2) -c2ccccc2) c1C

Molecular Formula

C31H33N5O2S

Molecular Weight

539.69

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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