LOX-IN-3 dihydrochloride
LOX-IN-3 dihydrochloride is a small molecule inhibitor of lysyl oxidase (LOX) and LOXL2, demonstrating potent activity with IC50 values below 10 μM and 1 μM for the bovine and human enzymes, respectively. This compound is a valuable research tool for studying extracellular matrix remodeling, fibrosis, and cancer metastasis in both cellular and animal models.
Product Specifications
CAS Number
2409964-23-2
Product Name Alternative
LOX, LOX IN 3 dihydrochloride, LOX-IN-3, LOXIN3 dihydrochloride, LOX-IN-3 Dihydrochloride, LOXL2, inhibit, PXS-5505 (hydrochloride), oxidase, lysyl, Inhibitor, Monoamine Oxidase, MAO, fibrosis
Field of Research
Metabolism Research, Neuroscience
Purity
99.86% (May vary between batches)
Solubility
DMSO:55 mg/mL (155.7 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.66 mM)
Smiles
Cl.Cl.NC\C=C (/F) CS (=O) (=O) c1cccc2cccnc12
Molecular Formula
C13H15Cl2FN2O2S
Molecular Weight
353.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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