MONIRO-1
MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively. MONIRO-1 has low activity against L-type calcium channels. MONIRO-1 can be used for the study of pain and epilepsy[1].
Product Specifications
CAS Number
1909225-94-0
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/moniro-1.html
Purity
99.18
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
N/C(N)=N\CCCOC1=CC=C(C=C1)C(NC2=C(C=CC=C2)OC3=CC=C(C=C3)F)=O.Cl
Molecular Formula
C23H24ClFN4O3
Molecular Weight
458.91
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
N-type calcium channel; T-type calcium channel
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Staphylococcus saprophyticus subsp. saprophyticus UPF0223 protein SSP1692 (SSP1692)
Recombinant Staphylococcus saprophyticus subsp. saprophyticus UPF0223 protein SSP1692 (SSP1692)