GW788388
GW788388 is a potent small molecule inhibitor primarily targeting ALK5 (TGF-β type I receptor), with additional activity against TGF-β type II and activin type II receptors. It is widely used in biochemical and cellular assays to study TGF-β and activin signaling pathways in fibrosis, cancer, and cardiovascular disease research, both in vitro and in vivo.
Product Specifications
CAS Number
452342-67-5
Product Name Alternative
ALK5, inhibit, GW788388, GW-788388, GW 788388, Inhibitor, Smad, TGFβ, TGF-β Receptor, TGF-β/Smad, TGF-beta, TGFbeta/Smad, TGF-b/Smad, TGFbeta, TGFb, Transforming growth factor beta receptors
Field of Research
Cardiovascular Research, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
TGFβ receptor inhibitor
Form
Powder
Solubility
Soluble in DMSO (40 mg/ml)
Smiles
O=C (NC1CCOCC1) c1ccc (cc1) -c1cc (ccn1) -c1c[nH]nc1-c1ccccn1
Molecular Formula
C25H23N5O2
Molecular Weight
425.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4- (4- (3- (Pyridin-2-yl) -1H-pyrazol-4-yl) pyridin-2-yl) -N- (tetrahydro-2H-pyran-4-yl) benzamide
Available Sizes
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