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N3-C3-NHS ester

The N3-C3-NHS ester is a non-cleavable linker used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy. Its stable design ensures the cytotoxic payload remains attached to the antibody during circulation, making it suitable for both in vitro biochemical studies and in vivo preclinical research models.

Product Specifications

CAS Number

943858-70-6

Product Name Alternative

Inhibit, Non-cleavable, N3 C3 NHS ester, N3C3NHS ester, N-3-C3-NHS ester, N3-C3-NHS ester, Inhibitor, Antibody-drug conjugates linkers, ADCLinker, ADC Linkers, ADC Linker

Field of Research

Pharmacology & Drug Discovery

Purity

95.00% (May vary between batches)

Solubility

DMSO:100 mg/mL (442.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (17.68 mM)

Smiles

[N-]=[N+]=NCCCC (=O) ON1C (=O) CCC1=O

Molecular Formula

C8H10N4O4

Molecular Weight

226.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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