N3-C3-NHS ester
The N3-C3-NHS ester is a non-cleavable linker used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy. Its stable design ensures the cytotoxic payload remains attached to the antibody during circulation, making it suitable for both in vitro biochemical studies and in vivo preclinical research models.
Product Specifications
CAS Number
943858-70-6
Product Name Alternative
Inhibit, Non-cleavable, N3 C3 NHS ester, N3C3NHS ester, N-3-C3-NHS ester, N3-C3-NHS ester, Inhibitor, Antibody-drug conjugates linkers, ADCLinker, ADC Linkers, ADC Linker
Field of Research
Pharmacology & Drug Discovery
Purity
95.00% (May vary between batches)
Solubility
DMSO:100 mg/mL (442.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (17.68 mM)
Smiles
[N-]=[N+]=NCCCC (=O) ON1C (=O) CCC1=O
Molecular Formula
C8H10N4O4
Molecular Weight
226.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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